4-(1H-苯并[D]咪唑-2-基)哌啶-1-羧酸叔丁酯

4-(1H-苯并[D]咪唑-2-基)哌啶-1-羧酸叔丁酯 - Names and Identifiers

Name	tert-butyl 4-(1H-benzo[d]iMidazol-2-yl)piperidine-1-carboxylate
Synonyms	Bilastine Impurity tert-Butyl 4-(1H-benzimidazol-2-yl)piperidine-1-carboxylate tert-butyl 4-(1H-benzo[d]iMidazol-2-yl)piperidine-1-carboxylate 2-Methyl-2-propanyl 4-(1H-benzimidazol-2-yl)-1-piperidinecarboxylate 1-Piperidinecarboxylic acid, 4-(1H-benzimidazol-2-yl)-, 1,1-dimethylethyl ester
CAS	953071-73-3

4-(1H-苯并[D]咪唑-2-基)哌啶-1-羧酸叔丁酯 - Physico-chemical Properties

Molecular Formula	C17H23N3O2
Molar Mass	301.38342
Density	1.184±0.06 g/cm3(Predicted)
Boling Point	497.1±38.0 °C(Predicted)
pKa	11.83±0.10(Predicted)
Storage Condition	Room Temprature
Use	Use 4-(1H-benzo [D] imidazol-2-yl) piperidine -1-carboxylic acid tert-butyl ester as Carboxylic Acid Ester derivatives, can be used as pharmaceutical intermediates.

4-(1H-苯并[D]咪唑-2-基)哌啶-1-羧酸叔丁酯 - Upstream Downstream Industry

Raw Materials

2-PIPERIDIN-4-YL-1H-BENZOIMIDAZOLE
1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde
N-BOC-piperidine-4-carboxylic acid
Di-tert-butyl dicarbonate
2-Nitroaniline
Isonipecotic acid
o-Phenylenediamine

4-(1H-苯并[D]咪唑-2-基)哌啶-1-羧酸叔丁酯 - Introduction

Tetra-tert-butyl 4-(LH-benzo [D] imidazol-2-yl) piperidine-L-carboxylate is an organic compound with the formula C22H32N4O2.

Nature:
Tetra-tert-butyl 4-(1H-benzo [D] imidazol-2-yl) piperidine-1-carboxylate is a solid with a white or off-white appearance. It has good stability at room temperature and is soluble in common organic solvents such as chloroform, dimethyl sulfoxide and dichloromethane.

Use:
Tetra-tert-butyl 4-(1H-benzo [D] imidazol-2-yl) piperidine -1-carboxylate is an important organic synthesis intermediate. It is often used as a starting material for the synthesis of drugs and other organic compounds. It can be used in the preparation of anti-epileptic drugs, anti-anxiety drugs, anti-depressant drugs, etc.

Method:
The preparation method of tetra-tert-butyl 4-(1H-benzo [D] imidazol-2-yl) piperidine -1-carboxylate is usually through amino protection, alkylation, acylation and a series of chemical reactions are completed.

Safety Information:
Tetra-tert-butyl 4-(1H-benzo [D] imidazol-2-yl) piperidine -1-carboxylate is generally considered to be relatively safe. However, as a chemical substance, it is still necessary to take appropriate safety measures in use and storage. Avoid inhalation, contact with skin and eyes, and keep away from fire and high temperature. Wear appropriate personal protective equipment such as gloves, goggles and protective clothing during use. Observe local regulations and safe operating guidelines during handling and disposal.

Last Update：2024-04-09 02:00:50